Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. N-phenylthioureas
  8. NS 11021, Tocris Bioscience™

NS 11021, Tocris Bioscience™
GREENER_CHOICE

Catalog No. p-4816584
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Activator of BKCa (KCa1.1) channels

Activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1). Exhibits no modulatory effect on a variety of K+ (KV), Na+ and Ca2+ currents at concentrations <10 μM. Alters gating kinetics, but does not affect single channel conductance. Shown to bind BKCa in open and closed conformations; thought to bind the α subunit.

Chemical Identifiers

CAS 956014-19-0
Molecular Formula C16H9BrF6N6S
Molecular Weight (g/mol) 511.244
InChI Key MDKAFDIKYQMOMF-UHFFFAOYSA-N
Synonym 1-3,5-bis trifluoromethyl phenyl-3-4-bromo-2-2h-tetrazol-5-yl phenyl thiourea, 1-3,5-bis-trifluoromethyl-phenyl-3-4-bromo-2-1h-tetrazol-5-yl-phenyl-thiourea, thiourea, n'-3,5-bis trifluoromethyl phenyl-n-4-bromo-2-2h-tetrazol-5-yl phenyl, n'-3,5-bis trifluoromethyl phenyl-n-4-bromo-2-2h-tetrazol-5-yl phenyl-thiourea, n'-3,5-bis trifluoromethyl phenyl-n-4-bromo-2-2h-tetrazol-5-yl-phenyl thiourea, 1-3,5-bis trifluoromethyl phenyl-3-4-bromo-2-1h-1,2,3,4-tetrazol-5-yl phenyl thiourea, 1-3,5-bis trifluoromethyl phenyl-3-4-bromo-2-2h-1,2,3,4-tetrazol-5-yl phenyl thiourea, 3-3,5-bis trifluoromethyl phenyl-1-4-bromo-2-1h-1,2,3,4-tetrazol-5-yl phenyl thiourea, 3-3,5-bis trifluoromethyl phenyl-1-4-bromo-2-2h-1,2,3,4-tetrazol-5-yl phenyl thiourea
PubChem CID 24825677
IUPAC Name 1-[3,5-bis(trifluoromethyl)phenyl]-3-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]thiourea
SMILES C1=CC(=C(C=C1Br)C2=NNN=N2)NC(=S)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

Specifications

Quantity 10 mg
Formula Weight 511.24
Percent Purity >98%
Chemical Name or Material NS 11021

Safety and Handling

Recommended Storage Store at -20°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.