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        Tocris Bioscience™ NS 2028
    
    
    
    
    
    
    
    
    
    
        
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                                Quantity:
                            
                        
                        
                            
                                10 mg
                            
                        
                            
                                50 mg
                            
                        
                    Description
Potent soluble guanylyl cyclase (sGC) inhibitor (Ki = 8 nM). Blocks sGC activity in murine cerebellum induced by S-nitroso-glutathione and NMDA (IC50 values are 17 and 20 nM respectively). Inhibits VEGF-induced cGMP accumulation; abolishes VEGF-induced migration in postcapillary venular endothelial cells (CVEC).
                        
                        
                        
                        
                        
                        
                        
                        
                        
                    
                
                
                    
                
                
    
                
    
            Specifications
Specifications
| Quantity | 10 mg | 
| Formula Weight | 269.05 | 
| Purity | >98% | 
| Molecular Weight (g/mol) | 269.05 | 
| Chemical Name or Material | NS 2028 | 
Safety and Handling
| Recommended Storage | Store at +4°C | 
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