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Tocris Bioscience™ NSC 74859
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Catalog No. 465550
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Catalog No. Quantity
46-555-0 50 mg
46-551-0 10 mg
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Catalog No. 46-555-0 Supplier Tocris Bioscience™ Supplier No. 4655/50
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Description

Selective STAT3 inhibitor

NSC 74859 selectively inhibits STAT3 DNA-binding activity in vitro (IC50 values are 86, 160, and >300 μM for STAT3-STAT3, STAT1-STAT3 and STAT1-STAT1 DNA-binding activity respectively). NSC 74859 blocks growth and induces apoptosis preferentially in tumor cells that contain persistently active STAT3 in vitro and arrests tumor growth in a murine xenograft model in vivo.

Chemical Identifiers

CAS 501919-59-1
Molecular Formula C16H15NO7S

Specifications

Quantity 50 mg
Formula Weight 365.36
Purity >98%
Molecular Weight (g/mol) 365.356
Chemical Name or Material NSC 74859

Safety and Handling

Recommended Storage Store at -20°C
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