NSMCE2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 136271AP150UL

Catalog No. 50-172-8888

Description

This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.

Specifications

• Antigen: NSMCE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NSMCE2
• Gene Alias: C8orf36, E3 SUMO protein ligase NSE2, hMMS21, MMS21, MMS21 homolog, Non SMC element 2 homolog, NSE2, NSMCE2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 286053, 299957, 68501
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 0.13 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q4V8A0, Q91VT1, Q96MF7
• Gene Symbols: NSMCE2
• Immunogen: NSMCE2 Fusion Protein Ag4545
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG