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NUMBL Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Description
The recommended shelf life for this product is 1 year from date of receipt.
The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.
Specifications
Specifications
| Antigen | NUMBL |
| Applications | Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 1 mg/ml |
| Conjugate | Unconjugated |
| Formulation | phosphate, tris citrate with 0.09% sodium azide; pH 7-8 |
| Gene | NUMBL |
| Gene Accession No. | Q9Y6R0 |
| Gene Alias | CAG3A, CTG3a, NBL, NUMB-R, NUMBLIKE, NUMBR, TNRC23, numb homolog-like; numb-like protein; numb-related protein |
| Gene Symbols | NUMBL |
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