O-GlcNAc Monoclonal Antibody (CTD110.6), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 61454

Catalog No. 50-199-3411

Description

O-linked N-acetylglucosamine (O-GlcNAc) is a posttranslational modification characterized by the attachment of N-acetylglucosamine to specific serine or threonine residues. Unlike other protein glycosylations, O-GlcNAc modifications occur within the nucleus and cytoplasm. They are found on many cellular proteins, including nuclear pore, oncogene, cytoskeletal, heat shock, viral and transcription regulatory proteins. O-GlcNAc glycosylations are thought to obscure phosphorylation sites, counteracting phosphorylation-dependent signaling pathways and protein interactions.

Specifications

• Antigen: O-GlcNAc
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Host Species: Mouse
• Purification Method: IgM
• Regulatory Status: RUO
• Target Species: Human, Multi-species, Mouse, Rat
• Product Type: Antibody
• Isotype: IgM

• Applications: Immunoprecipitation, Western Blot
• Clone: CTD110.6
• Conjugate: Unconjugated
• Gene Alias: GlcNAc
• Immunogen: This antibody was raised against a peptide containing O-GlcNAc - serine. This antibody recognizes single O-GlcNAc residues in b-O-glycosidic linkage to serine and threonine.
• Quantity: 10 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid