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Obinutuzumab Mouse, Clone: 16B7, GenScript™

Catalog No. 502120668
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50-212-0668 40 μg
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Catalog No. 50-212-0668 Supplier Genscript Corporation Supplier No. A0194640
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Description

Mouse Monoclonal Antibody

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. Obinutuzumab is a humanized anti-CD20 monoclonal antibody, originated by GlycArt Biotechnology AG and developed by Roche as a cancer treatment. It was approved under the trade name Gazyva by the US FDA in 2013, and as Gazyvaro by the EMA in Europe, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients, and as a second line treatment for follicular lymphoma. Obinutuzumab is a fully humanized monoclonal antibody that binds to an epitope on CD20 that partially overlaps with the epitope recognized by rituximab. Obinutuzumab binds to CD20 on B cells and causes these cells to be destroyed by engaging the adaptive immune system, directly activating intracellular apoptosis pathways, and activating the complement system.

Obinutuzumab Monoclonal antibody specifically detects Obinutuzumab in Chemical samples. It is validated for ELISA

Specifications

Antigen Obinutuzumab
Applications ELISA
Classification Monoclonal
Clone 16B7
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide; pH 7.4
Gene Alias Gazyva; Gazyvaro
Host Species Mouse
Immunogen Obinutuzumab
Purification Method Protein A
Quantity 40 μg
Regulatory Status RUO
Primary or Secondary Primary
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Lyophilized
Isotype IgG2a κ
Target Molecule Chemical
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