Optineurin Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301831A

Catalog No. 50-156-1097

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Specifications

• Antigen: Optineurin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: OPTN
• Gene Alias: ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP, E3-14.7K-interacting protein, FIP-2, HIP-7, Huntingtin interacting protein L, huntingtin yeast partner L, huntingtin-interacting protein 7, huntingtin-interacting protein L, nemo-related protein, optic neuropathy-inducing protein, transcription factor IIIA-interac, Uban
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10133
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q96CV9
• Gene Symbols: OPTN
• Immunogen: Between 504 and 554
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG