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Invitrogen™ ORC6 Polyclonal Antibody
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Catalog No. PIPA5120914
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PIPA5120914 100 μL
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Catalog No. PIPA5120914 Supplier Invitrogen™ Supplier No. PA5120914
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Description

Rabbit Polyclonal Antibody

Positive test controls include: Jurkat, SW620, PC-3, HeLa, Mouse brain, Rat brain. The target is usually found in the following locations: Nucleus. Immunogen sequence: MGSELIGRLA PRLGLAEPDM LRKAEEYLRL SRVKCVGLSA RTTETSSAVM CLDLAASWMK CPLDRAYLIK LSGLNKETYQ SCLKSFECLL GLNSNIGIRD LAVQFSCIEA VNMASKILKS YESSLPQTQQ VDLDLSRPLF TSAALLSACK ILKLKVDKNK MVATSGVKKA IFDRLCKQLE KIGQQVDREP GDVATPPRKR KKIVVEAPAK EMEKVEEMPH KPQKDEDLTQ DYEEWKRKIL ENAASAQKAT AE.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ORC6
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.56 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Orc6
Gene Accession No. Q9WUJ8, Q9Y5N6
Gene Alias 6720420I10Rik; ORC 6; ORC6; ORC6L; origin recognition complex subunit 6; origin recognition complex, subunit 6; origin recognition complex, subunit 6-like
Gene Symbols Orc6
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-252 of human ORC6 (NP_055136.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23594, 291927, 56452
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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