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Ornithine Decarboxylase Antibody (ODC1/485), HRP, Novus Biologicals™
SDP

Catalog No. NBP234700H Shop All R&D Systems Products
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NBP234700H 0.1 mL
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Catalog No. NBP234700H Supplier Novus Biologicals Supplier No. NBP234700H
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Description

Mouse Monoclonal Antibody

Ornithine Decarboxylase Monoclonal specifically detects Ornithine Decarboxylase in Human, Mouse, Rat samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Ornithine Decarboxylase
Applications Western Blot, ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
Clone ODC1/485
Conjugate HRP
Dilution Western Blot, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1
Gene Symbols ODC1
Host Species Mouse
Immunogen Recombinant full-length human Ornithine Decarboxylase protein (Uniprot: P11926)
Molecular Weight of Antigen 53 kDa
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cell Cycle and Replication
Primary or Secondary Primary
Gene ID (Entrez) 4953
Test Specificity Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
Target Species Human, Rat
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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