Ornithine Decarboxylase Mouse, Clone: ODC1/485, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 1 publication

Supplier:  Novus Biologicals NBP2328870.2MG

Catalog No. NBP232887B

Description

Ornithine Decarboxylase Monoclonal antibody specifically detects Antigen in Human, Rat samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blotting.

Specifications

• Antigen: Ornithine Decarboxylase
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: ODCEC 4.1.1.17, ornithine decarboxylase, ornithine decarboxylase 1
• Host Species: Mouse
• Molecular Weight of Antigen: 53 kDa
• Quantity: 0.2 mg
• Research Discipline: Cell Cycle and Replication
• Gene ID (Entrez): 4953
• Target Species: Human, Rat
• Form: Purified

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
• Clone: ODC1/485
• Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, SDS-Page, Immunofluorescence
• Gene Accession No.: P11926
• Gene Symbols: ODC1
• Immunogen: Recombinant human ODC-1 protein
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
• Content And Storage: Store at 4C.
• Isotype: IgG1 κ