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OX40/TNFRSF4 Antibody (7D6), Allophycocyanin/Cy7
SDP

Catalog No. N1064375AP7 Shop All R&D Systems Products
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N1064375AP7 0.1 mL
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Catalog No. N1064375AP7 Supplier Novus Biologicals Supplier No. NB10064375APCCY7

Description

Mouse Monoclonal Antibody

OX40/TNFRSF4 Monoclonal specifically detects OX40/TNFRSF4 in Feline samples. It is validated for Flow Cytometry.

Specifications

Antigen OX40/TNFRSF4
Applications Flow Cytometry
Classification Monoclonal
Clone 7D6
Conjugate APC-Cyanine7
Dilution Flow Cytometry
Formulation PBS with 0.05% Sodium Azide
Gene Alias ACT35 antigen, ACT35ATC35 antigen, CD134, CD134 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, OX40lymphoid activation antigene ACT35, TAX transcriptionally-activated glycoprotein 1 receptor, tax-transcriptionally activated glycoprotein 1 receptor, tumor necrosis factor receptor superfamily member 4, tumor necrosis factor receptor superfamily, member 4, TXGP1LOX40 antigen
Gene Symbols TNFRSF4
Host Species Mouse
Immunogen CHO-derived feline CD134-Fc fusion protein.
Purification Method Protein A purified
Quantity 0.1 mL
Research Discipline Adaptive Immunity, B Cell Development and Differentiation Markers, Cancer, Cell Cycle and Replication, Immunology, Myeloid derived Suppressor Cell, Signal Transduction
Primary or Secondary Primary
Gene ID (Entrez) 7293.0
Test Specificity NB100-64375 recognizes feline CD134, otherwise known as OX40, a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells.
Target Species Feline
Content And Storage Store at 4°C in the dark. Do not freeze.
Isotype IgG1
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