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Tocris Bioscience™ P 22077
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Catalog No. 448510
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44-851-0 10 mg
44-855-0 50 mg
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Catalog No. 44-851-0 Supplier Tocris Bioscience™ Supplier No. 4485/10
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Description

USP7 inhibitor

Inhibitor of ubiquitin-specific protease (USP) 7 (EC50 = 8.6 μM); also inhibits the closely related deubiquitinase (DUB) USP47. Demonstrates downstream inhibition of HDM2 and claspin in vitro. Inhibits USP7-mediated p53 deubiquitination. Blocks deubiquitination of Tip60 (KAT5) histone lysine acetyltransferase.

Chemical Identifiers

CAS 1247819-59-5
Molecular Formula C12H7F2NO3S2

Specifications

Quantity 10 mg
Formula Weight 315.32
Purity >99%
Molecular Weight (g/mol) 315.31
Chemical Name or Material P 22077

Safety and Handling

Recommended Storage Store at +4°C
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