Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic Compounds
  5. Organosulfur compounds
  6. Thioethers
  7. Aryl thioethers
  8. Diarylthioethers
  9. P 22077, Tocris Bioscience™

P 22077, Tocris Bioscience™

Click to view available options
Quantity:
10mg
50mg
This item is not returnable. View return policy
1247819-59-5
C12H7F2NO3S2
315.309
RMAMGGNACJHXHO-UHFFFAOYSA-N
1-5-2,4-difluorophenyl thio-4-nitro-2-thienyl-ethanone,1-5-2,4-difluoro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone,1-5-2,4-difluorophenylthio-4-nitrothiophen-2-yl ethanone,1-5-2,4-difluorophenyl thio-4-nitrothiophen-2-yl ethan-1-one,1-5-2,4-difluorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one,1-5-2,4-difluorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone,1-5-2,4-difluorophenyl thio-4-nitro-2-thienyl ethanon
46931953
1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone
CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-]
This item is not returnable. View return policy
1247819-59-5
C12H7F2NO3S2
315.309
RMAMGGNACJHXHO-UHFFFAOYSA-N
1-5-2,4-difluorophenyl thio-4-nitro-2-thienyl-ethanone,1-5-2,4-difluoro-phenylsulfanyl-4-nitro-thiophen-2-yl-ethanone,1-5-2,4-difluorophenylthio-4-nitrothiophen-2-yl ethanone,1-5-2,4-difluorophenyl thio-4-nitrothiophen-2-yl ethan-1-one,1-5-2,4-difluorophenyl sulfanyl-4-nitrothiophen-2-yl ethan-1-one,1-5-2,4-difluorophenyl sulfanyl-4-nitrothiophen-2-yl ethanone,1-5-2,4-difluorophenyl thio-4-nitro-2-thienyl ethanon
46931953
1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone
CC(=O)C1=CC(=C(S1)SC2=C(C=C(C=C2)F)F)[N+](=O)[O-]

Description

USP7 inhibitor

Inhibitor of ubiquitin-specific protease (USP) 7 (EC50 = 8.6 μM); also inhibits the closely related deubiquitinase (DUB) USP47. Demonstrates downstream inhibition of HDM2 and claspin in vitro. Inhibits USP7-mediated p53 deubiquitination. Blocks deubiquitination of Tip60 (KAT5) histone lysine acetyltransferase.
Quantity 50mg
Formula Weight 315.32
Percent Purity >99%
Chemical Name or Material P 22077

Safety and Handling

Recommended Storage : Store at +4°C