P5CS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 177191AP
DescriptionThis gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|ALDH18A1, GK, GPR, GSAS, P5CS, PYCS|
|361755, 56454, 5832|
|Immunoprecipitation, Western Blot|
|P5CS Fusion Protein Ag12100|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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