P62/SQSTM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-553-750	Proteintech Group Inc 184201AP150UL	150 μL

Description

The molecular weight of p62 is predicted to be 48/ 38 kDa (depending on the isoform), while western blot analyses using this antibody detects the bands around 45-48 kDa and 60-62 kDa, respectively.

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Specifications

• Antigen: P62/SQSTM1
• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O08623, Q13501, Q64337
• Gene ID (Entrez): 113894, 18412, 8878
• Immunogen: P62/SQSTM1 Fusion Protein Ag13131
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SQSTM1

• Concentration: 0.29 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: P62, sequestosome 1, SQSTM1, Ubiquitin binding protein p62
• Gene Symbols: Sqstm1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody