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  7. PAC 1, Tocris Bioscience™

PAC 1, Tocris Bioscience™

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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
315183-21-2
C23H28N4O2
392.50
MFCD03302441
XSGXRYNZNGUGEJ-UHFFFAOYSA-N
pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide
6851947
2-(4-benzylpiperazin-1-yl)-N'-{[6-oxo-5-(prop-2-en-1-yl)cyclohexa-2,4-dien-1-ylidene]methyl}acetohydrazide
C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC3=CC=CC=C3)CC2)C1=O
This item is not returnable. View return policy
315183-21-2
C23H28N4O2
392.50
MFCD03302441
XSGXRYNZNGUGEJ-UHFFFAOYSA-N
pac-1, procaspase-3 activator, procaspase activating compound 1, procaspase-3 activator, pac-1, 4-benzylpiperazino acetic acid-3-allyl-2-hydroxybenzylidene hydrazide, 2-4-benzylpiperazin-1-yl-n'-z-6-oxo-5-prop-2-enylcyclohexa-2,4-dien-1-ylidene methyl acetohydrazide, d01yif, e-n'-3-allyl-2-hydroxybenzylidene-2-4-benzylpiperazin-1-yl acetohydrazide, 2-4-benzylpiperazin-1-yl-n'-1e-2-hydroxy-3-prop-2-en-1-yl phenyl methylidene acetohydrazide, 4-phenylmethyl-1-piperazineacetic acid 2-hydroxy-3-2-propenyl phenyl methylene hydrazide
6851947
2-(4-benzylpiperazin-1-yl)-N'-{[6-oxo-5-(prop-2-en-1-yl)cyclohexa-2,4-dien-1-ylidene]methyl}acetohydrazide
C=CCC1=CC=CC(=CNNC(=O)CN2CCN(CC3=CC=CC=C3)CC2)C1=O

Description

Activator of procaspase-3; pro-apoptotic

Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 μM). Also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). Pro-apoptotic; induces apoptosis in both cancerous and non-cancerous cells dependent on procaspase-3 concentration (IC50 values are 0.003 - 1.41 and 5.02 - 9.98 μM respectively).
Quantity 10 mg
Formula Weight 392.5
Percent Purity >98%
Chemical Name or Material PAC 1

Safety and Handling

Recommended Storage : Store at +4°C

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