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PARN Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7205741 Shop All Proteintech Group Inc Products
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50-172-9015 150 μL
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Catalog No. 50-172-9015 Supplier Proteintech Group Inc Supplier No. 137991AP150UL
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Rabbit Polyclonal Antibody

The protein encoded by this gene is a 3′-exoribonuclease, with similarity to the RNase D family of 3′-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen PARN
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene PARN
Gene Accession No. O95453, Q8VDG3
Gene Alias DAN, Deadenylating nuclease, Deadenylation nuclease, PARN
Gene Symbols Parn
Host Species Rabbit
Immunogen PARN Fusion Protein Ag4774
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 360464, 5073, 74108
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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