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Pax6 Mouse, Clone: PAX6/496, Novus Biologicals™
SDP

Mouse Monoclonal Antibody has been used in 1 publication

Supplier:  Novus Biologicals NBP2328930.1MG

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Catalog No. NBP232893A


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Description

Description

Pax6 Monoclonal specifically detects Pax6 in Human, Mouse, Rat, Chicken samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Flow (Intracellular).
Specifications

Specifications

Pax6
Monoclonal
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
keratitis), MGC17209, Oculorhombin, paired box 6, paired box protein Pax-6
Mouse
47 kDa
0.1 mg
Cellular Markers, Diabetes Research, Neuronal Stem Cell Markers, Neuroscience, Sensory Systems, Stem Cell Markers, Stem Cells, Transcription Factors and Regulators, Vision
5080
Human, Mouse, Rat, Chicken
Purified
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
PAX6/496
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml
P26367
PAX6
Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
Protein A purified
RUO
Primary
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Store at 4C.
IgG1 κ
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