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PD-1 Antibody (SPM597), Alexa Fluor™ 750, Novus Biologicals™
SDP

Catalog No. NP247806A70 Shop All R&D Systems Products
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NP247806A70 0.1 mL
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Catalog No. NP247806A70 Supplier Novus Biologicals Supplier No. NBP247806AF750
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Description

Mouse Monoclonal Antibody

PD-1 Monoclonal specifically detects PD-1 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

Antigen PD-1
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
Clone SPM597
Conjugate Alexa Fluor 750
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Formulation 50 mM sodium borate with 0.05% sodium azide
Gene Alias CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
Gene Symbols PDCD1
Host Species Mouse
Immunogen Recombinant full-length human PD-1 protein (Uniprot: Q15116)
Quantity 0.1 mL
Primary or Secondary Primary
Gene ID (Entrez) 5133
Test Specificity PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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