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PD 146176, Tocris Bioscience™
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Quantity:
10 mg
50 mg
Description
Specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM) that has no demonstrable effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC50 = 0.54 μM for 15-LOX in rabbit reticulocytes). Lacks non-specific antioxidant properties and prevents atherogenesis via regulation of monocyte-macrophage enrichment in vivo.
Specifications
Quantity | 10 mg |
Formula Weight | 237.32 |
Percent Purity | >98% |
Chemical Name or Material | PD 146176 |
Safety and Handling
Recommended Storage : Store at +4°C