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  5. Tocris Bioscience™ PD 166285 dihydrochloride

Tocris Bioscience™ PD 166285 dihydrochloride
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Catalog No. 37851
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37-851 1 mg
37-851-0 10 mg
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Catalog No. 37-851 Supplier Tocris Bioscience™ Supplier No. 3785/1
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Description

Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1

Potent inhibitor of the tyrosine kinases c-Src, fibroblast growth factor receptor 1 (FGFR1), and platelet-derived growth factor receptor β (PDGFRβ) (IC50 values are 8.4, 39.3 and 98.3 nM respectively). Also inhibits the checkpoint kinases Wee1 and Myt1; abolishes Cdc2 phosphorylation in numerous tumor cell lines and abrogates the G2 checkpoint.

Chemical Identifiers

CAS 212391-63-4
Molecular Formula C26H29Cl4N5O2

Specifications

Quantity 1 mg
Formula Weight 585.35
Purity >99%
Molecular Weight (g/mol) 585.351
Chemical Name or Material PD 166285 dihydrochloride

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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