Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 260510

Tocris Bioscience™ PD 198306
GREENER_CHOICE

Catalog No. 260510
Change view
Click to view available options
Quantity:
10 mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
26-051-0 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Catalog No. 26-051-0 Supplier Tocris Bioscience™ Supplier No. 2605/10
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

Selective inhibitor of MEK1/2

Potent inhibitor of MEK1/2. Inhibits isolated enzyme at a concentration of 8 nM and inhibits MEK activity in synovial fibroblasts at concentrations of 30 - 100 nM. Highly selective for MEK; IC50 values are > 1, > 4, > 4 and > 10 μM for ERK, c-Src, cdks and PI 3-kinase γ respectively. Antihyperalgesic; blocks static allodynia in the streptozocin model of neuropathic pain following i.t. administration.

Chemical Identifiers

CAS 212631-61-3
Molecular Formula C18H16F3IN2O2

Specifications

Quantity 10 mg
Formula Weight 476.23
Purity >98%
Molecular Weight (g/mol) 476.238
Chemical Name or Material PD 198306

Safety and Handling

Recommended Storage Store at +4°C
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.