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PD-L2/B7-DC/PDCD1LG2 Antibody (TY25), Alexa Fluor™ 488, Novus Biologicals™
SDP

Catalog No. NB165332AG Shop All R&D Systems Products
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0.125 mL
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Catalog No. Quantity
NB165332AG 0.125 mL
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Catalog No. NB165332AG Supplier Novus Biologicals Supplier No. NB10065332AF488

Description

Rat Monoclonal Antibody

PD-L2/B7-DC/PDCD1LG2 Monoclonal specifically detects PD-L2/B7-DC/PDCD1LG2 in Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen.

Specifications

Antigen PD-L2/B7-DC/PDCD1LG2
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone TY25
Conjugate Alexa Fluor 488
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2
Gene Symbols PDCD1LG2
Host Species Rat
Immunogen B7-DC transfected RAW264.7 cells.
Purification Method Protein G purified
Quantity 0.125 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80380
Test Specificity NB100-65332 recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD274). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to it's receptor.
Target Species Mouse
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG2a
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