Invitrogen™ PDE3B Recombinant Rat Monoclonal Antibody (SMCP3B)

Rat Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
74-006-9T	Invitrogen™ 740069T	100 μL
74-006-9TXS	Invitrogen™ 740069TXS	20 μL

Description

Recombinant rat monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include better specificity and lot-to-lot consistency. Applications Tested: This SMCP3B antibody has been tested in western blot and immunoprecipitation in 3T3-L1 Adipocyte differentiated cells. It can be used at 1 μg/mL in western blot and 10 μg in immunoprecipitation. This antibody may result in detection of non-specific bands in western blot application along with the band of interest. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Specifications

• Antigen: PDE3B
• Concentration: 1.0 mg/mL
• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rat
• Regulatory Status: RUO
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q61409
• Gene ID (Entrez): 18576
• Primary or Secondary: Primary
• Purification Method: Affinity Chromatography

• Clone: SMCP3B
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Classification: Recombinant Monoclonal
• Form: Liquid
• Isotype: IgG2a κ
• Target Species: Mouse
• Gene: PDE3B
• Gene Alias: 9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
• Gene Symbols: PDE3B
• Product Type: Antibody