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PDE4B Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
$191.80
Specifications
Antigen | PDE4B |
---|---|
Concentration | 0.5 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot, Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
FEPA5145430
|
Invitrogen™
PA5145430 |
20 μL |
Each for $191.80
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FEPA5145429
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Thermo Scientific
PA5145429 |
200 μL | N/A | N/A | N/A | ||||
Description
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Specifications
PDE4B | |
Immunohistochemistry (Paraffin), Western Blot, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
P14646, Q07343 | |
18578, 24626, 5142 | |
Recombinant Rat PDE4B protein, Lys500-Thr736 (Accession #P14646). | |
Primary | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
0.5 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4 | |
3',5'-cyclic AMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DKFZp686F2182; DPDE4; dunce; dunce-like phosphodiesterase E4; MGC126529; MGC93193; OTTHUMP00000046896; PDE32; PDE4/IVb; PDE4B; Pde4B1; Pde4B2; Pde4B3; Pde4B4; PDEIVB; phosphodiesterase 4B; Phosphodiesterase 4B cAMP-specific (dunce; phosphodiesterase 4B, cAMP specific; phosphodiesterase 4B, cAMP-specific; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); R74983; RP5-876C12.1 | |
PDE4B | |
IgG | |
Protein A | |
PDE4B |
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