PDE8A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9119	150 μL

Catalog No. 50-172-9119 Supplier Proteintech Group Inc Supplier No. 139561AP150UL

Description

Rabbit Polyclonal Antibody

PDE8A is a Phosphodiesterase (PDEs), which regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (MIM 2000).

Specifications

• Antigen: PDE8A
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.42 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: PDE8A
• Gene Accession No.: O60658, O88502
• Gene Alias: HsT19550, PDE8A, phosphodiesterase 8A
• Gene Symbols: Pde8a
• Host Species: Rabbit
• Immunogen: PDE8A Fusion Protein Ag5069
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18584, 308776, 5151
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG