PDE8A Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-172-9119	Proteintech Group Inc 139561AP150UL	150 μL

Description

PDE8A is a Phosphodiesterase (PDEs), which regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling (MIM 2000).

Specifications

• Antigen: PDE8A
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse, Rat
• Gene Accession No.: O60658, O88502
• Gene ID (Entrez): 18584, 308776, 5151
• Immunogen: PDE8A Fusion Protein Ag5069
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: PDE8A

• Concentration: 0.42 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Alias: HsT19550, PDE8A, phosphodiesterase 8A
• Gene Symbols: Pde8a
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody