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Penitrem A, Tocris Bioscience™ Available on GSA/VA Contract for Federal Government customers only.

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Quantity:
1mg
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12627-35-9
C37H44ClNO6
634.21
JDUWHZOLEDOQSR-OGOYAGGGSA-N
penitrem a
122173132
CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8(C1=C7C(=CC(=C1CC9=C)Cl)N6)O)(C)C)C)O)C)O
This item is not returnable. View return policy
12627-35-9
C37H44ClNO6
634.21
JDUWHZOLEDOQSR-OGOYAGGGSA-N
penitrem a
122173132
CC(=C)C1C(C2C3(O2)C(O1)CCC4(C3(CCC5C4(C6=C7C5OC(C8CC9C8(C1=C7C(=CC(=C1CC9=C)Cl)N6)O)(C)C)C)O)C)O

Description

Potent and selective BKCa (KCa1.1) channel blocker

Potent and selective blocker of BKCa (KCa1.1) channels (IC50 values are 6.4 and 64.4 nM for BKCa channels containing α subunits only, and those containing α and β1 respectively). Displays no effect on native delayed rectifier K+ and KATP currents, or cloned KV1.5 channels. Blocks BKCa channels in both inside-out and cell-attached patches. Shown to enhance smooth muscle contraction in vitro and increase total peripheral resistance in vivo.

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Quantity 1mg
Formula Weight 634.2
Percent Purity >98%
Chemical Name or Material Penitrem A

Safety and Handling

Recommended Storage : Store at -20°C