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Tocris Bioscience™ Penitrem A

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Quantity:
1 mg
Description
Potent and selective blocker of BKCa (KCa1.1) channels (IC50 values are 6.4 and 64.4 nM for BKCa channels containing α subunits only, and those containing α and β1 respectively). Displays no effect on native delayed rectifier K+ and KATP currents, or cloned KV1.5 channels. Blocks BKCa channels in both inside-out and cell-attached patches. Shown to enhance smooth muscle contraction in vitro and increase total peripheral resistance in vivo.
Specifications
Specifications
Quantity | 1 mg |
Formula Weight | 634.2 |
Purity | >98% |
Molecular Weight (g/mol) | 634.21 |
Chemical Name or Material | Penitrem A |
Safety and Handling
Recommended Storage | Store at -20°C |
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