Perilipin-2/ADFP Antibody (ADFP/1494), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2545970.1MG

Catalog No. NB25459701

Description

Perilipin-2/ADFP Monoclonal specifically detects Perilipin-2/ADFP in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: Perilipin-2/ADFP
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin 2-4 ug/ml, Immunofluorescence 0.5-1.0 ug/ml
• Gene Alias: ADFP, Adipophilin, Adipose differentiation-related proteinadipophilin, ADRP, MGC10598, perilipin 2, perilipin-2
• Host Species: Mouse
• Molecular Weight of Antigen: 48 kDa
• Quantity: 0.1 mg
• Research Discipline: Cancer, Hypoxia, Lipid and Metabolism, Lipid Droplets, Signal Transduction
• Gene ID (Entrez): 123
• Target Species: Human
• Form: Purified

• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
• Clone: ADFP/1494
• Conjugate: Unconjugated
• Formulation: 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: PLIN2
• Immunogen: Recombinant human Adipophilin protein fragment (aa249-376) (exact sequence is proprietary)
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.
• Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Isotype: IgG2b κ

For Research Use Only