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Periplakin/PPL Rabbit anti-Human, Mouse, Rat, Polyclonal, Bethyl Laboratories

Catalog No. 501559000
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50-155-9000 100 μL
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Catalog No. 50-155-9000 Supplier Bethyl Laboratories, Inc Supplier No. A301005A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.

Specifications

Antigen Periplakin/PPL
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene PPL
Gene Accession No. O60437, Q9R269
Gene Alias 190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein
Gene Symbols Ppl
Host Species Rabbit
Immunogen Between 1150 and 1200
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19041, 302934, 5493
Target Species Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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