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Tocris Bioscience™ PF 06465469
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Catalog No. 471010
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Catalog No. Quantity
47-101-0 10 mg
47-105-0 50 mg
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Catalog No. 47-101-0 Supplier Tocris Bioscience™ Supplier No. 4710/10
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Description

Potent ITK inhibitor; also inhibits BTK

Potent inhibitor of interleukin-2 inducible T cell kinase (ITK) (IC50 = 2 nM). Also exhibits inhibitory activity against Bruton's tyrosine kinase (BTK) (IC50 = 2 nM). Displays nanomolar potencies in a cell-based IP1 assay and human whole blood assay (IC50 values are 31 and 48 nM respectively).

Chemical Identifiers

CAS 1407966-77-1
Molecular Formula C30H33N7O2

Specifications

Quantity 10 mg
Formula Weight 523.63
Purity >95%
Molecular Weight (g/mol) 523.641
Chemical Name or Material PF 06465469

Safety and Handling

Recommended Storage Store at +4°C
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