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Tocris Bioscience™ PF 915275
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Catalog No. 329150
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Quantity:
10 mg
50 mg
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Catalog No. 32-915-0

Supplier: Tocris Bioscience™ 3291/50

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Description

Potent and selective 11β-hydroxysteroid dehydrogenase inhibitor

Potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) that displays little activity at 11βHSD2 (1.5% inhibition at 10 μM). Inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo. Orally active.

Chemical Identifiers

CAS 857290-04-1
Molecular Formula C18H14N4O2S

Specifications

Quantity 50 mg
Formula Weight 350.39
Purity >98%
Molecular Weight (g/mol) 350.396
Chemical Name or Material PF 915275

Safety and Handling

Recommended Storage Store at Room Temperature
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