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Phc1 Monoclonal Antibody (6-1-3), Active Motif™
SDP

Mouse Monoclonal Antibody

$156.65 - $620.58

Specifications

Antigen Phc1
Clone 6-1-3
Concentration 1 mg/mL
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2806
SDP
Encompass
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Active Motif
39724
10 μg
Each for $156.65
Only null left
Add to Cart
 
50-199-2805
SDP
Encompass
View Documents
Active Motif
39723
100 μg
Each for $620.58
Only null left
Add to Cart
 
Description

Description

Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development. PHC1 (polyhomeotic homolog 1), also known as EDR1, HPH1 or RAE28, is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Specifications

Specifications

Phc1
1 mg/mL
Monoclonal
Liquid
RUO
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
AW557034; BOS_5916; DKFZp686A1782; early development regulator 1 (homolog of polyhomeotic 1); early development regulator1 (homolog of polyhomeotic 1); Early development regulatory protein 1; Edr; Edr1; hPH1; LOC100347568; MCPH11; mPH1; PH1; PHC1; polyhomeotic 1-like; polyhomeotic homolog 1; polyhomeotic homolog 1 (Drosophila); polyhomeotic-like 1; polyhomeotic-like 1 (Drosophila); Polyhomeotic-like protein 1; Rae28; RAE-28
PHC1
IgG
Protein G
Antibody
6-1-3
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
Mouse
Human, Mouse
P78364, Q64028
13619, 1911
This Phc1 antibody was raised against a recombinant mouse Phc1 protein fragment.
Primary
-20°C, Avoid Freeze/Thaw Cycles
PHC1
Videos
SDS
Documents

Documents

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