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PHIP Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 209331AP

Catalog No. 50-173-3162


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Description

Description

PHIP (pleckstrin homology domain interacting protein), also known as ndrp or WDR11, is a 1,821 amino acid protein that contains eight N-terminal WD40 repeats and two bromodomains. It is expressed in skeletal muscle (localizing to the cytosol and nucleus) and primary beta cells (localizing to the nucleus) and acts as a transcriptional activator. PHIP is known to interact with various members of the insulin receptor substrate (IRS) family. The IRS family of proteins mediate insulin receptor signaling and play an important role in insulin-producing beta cell proliferation and survival. PHIP specifically associates with the PH domain of IRS-1 and may function to link IRS-1 to insulin receptors, indicating a vital role of PHIP in the regulation of insulin signaling.
Specifications

Specifications

PHIP
0.82 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q8VDD9, Q8WWQ0
ndrp, PH interacting protein, PHIP, WDR11
Rabbit
IgG
150 μL
-20°C
Primary
55023, 83946
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
PHIP
Liquid
PHIP
PHIP Fusion Protein Ag14968
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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