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MP Biomedicals™ Phorbol-12-Myristate-13-Acetate, MP Biomedicals™

Promotes tumors and activates kinase C. Phorbol-12-Myristate-13-Acetate, MP Biomedicals is a diester of phorbol and a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vi

$520.00 - $1172.00

Specifications

For Use With (Application) PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
Format Colorless Material
Molecular Weight 616.84
Storage Requirements Store at −20°C, protect from light.
Purity >99%
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MP215186410 View Documents MP Biomedicals™
0215186410
10mg Each for $520.00
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MP215186425 View Documents MP Biomedicals™
0215186425
25mg Each for $1,172.00
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Description

Description

PMA’s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC. PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

Specifications

Specifications

PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
616.84
>99%
Colorless Material
Store at −20°C, protect from light.
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