MP Biomedicals™ Phorbol-12-myristate-13-acetate, >99%

Description

Phorbol-12-myristate-13-acetate, >99% is a potent tumor promoter and activates protein kinase C in vivo and in vitro.

• PMA′s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC.
• PMA activates Ca2+− ATPase and potentiates forskolin-induced cAMP formation.
• It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

Specifications

• Purity: >98% (HPLC)
• For Use With (Application): Potent tumor promoter, Activates protein kinase C in vivo and in vitro
• Solubility: Practically insoluble.
• Molecular Formula: C36H56O8
• CAS: 16561-29-8
• Content And Storage: Store at − 20°C. Protect from light.
• Quantity: 1 mg
• Molecular Weight (g/mol): 616.84 g/mol
• Melting Point: 162°F
• Vapor Pressure: 1.8X10-17 mm Hg at 25°C
• Form: Solid

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.