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MP Biomedicals™ Phorbol-12-Myristate-13-Acetate, MP Biomedicals™
Promotes tumors and activates kinase C. Phorbol-12-Myristate-13-Acetate, MP Biomedicals is a diester of phorbol and a tumor promoting compound extracted from croton oil. It is a reversible, highly potent protein kinase C (PKC) activator in vitro and in vi
$520.00 - $1172.00
Specifications
| For Use With (Application) | PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. |
|---|---|
| Format | Colorless Material |
| Molecular Weight | 616.84 |
| Storage Requirements | Store at −20°C, protect from light. |
| Purity | >99% |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
| MP215186410 |
MP Biomedicals™
0215186410 |
10mg |
Each for $520.00
|
|
MP215186425 |
MP Biomedicals™
0215186425 |
25mg |
Each for $1,172.00
|
|
Description
PMA’s effects on PKC are attributed to its similarity to diacylgylerol, a natural activator of PKC. PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
Specifications
| PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells. | |
| 616.84 | |
| >99% |
| Colorless Material | |
| Store at −20°C, protect from light. |
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