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  6. Invitrogen™ Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5)

Invitrogen™ Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5)

Catalog No. p-200121965
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200 μL
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PIMA527999 200 μL
PIMA536935 20 μL
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Catalog No. PIMA527999 Supplier Invitrogen™ Supplier No. MA527999
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E, which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-4EBP1 (Thr37, Thr46)
Applications Flow Cytometry, Immunohistochemistry, Western Blot
Classification Recombinant Monoclonal
Clone 4EB1T37T46-A5
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene EIF4EBP1
Gene Accession No. Q13541, Q60876, Q62622
Gene Alias 4EBP1; 4E-BP1; AA959816; BP-1; eIF4E-binding protein 1; EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; MGC431; MGC4316; P/OKCL.6; PHAS-1; PHAS-I; Phosphorylated heat- and acid-stable protein regulated by insulin 1
Gene Symbols EIF4EBP1
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116636, 13685, 1978
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG κ
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