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Invitrogen™ Phospho-BAD (Ser118) Polyclonal Antibody
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Catalog No. PIPA5105022
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100 μL
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PIPA5105022 100 μL
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Catalog No. PIPA5105022 Supplier Invitrogen™ Supplier No. PA5105022
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of BAD only when phosphorylated at Ser118, which site historically referenced as Ser155.

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-BAD (Ser118)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BAD
Gene Accession No. O35147, Q61337, Q92934
Gene Alias AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400
Gene Symbols BAD
Host Species Rabbit
Immunogen A synthesized peptide derived from human BAD(Accession Q92934), corresponding to amino acid residues around phosphorylated Ser118.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12015, 572, 64639
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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