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Invitrogen™ Phospho-BLNK (Tyr96) Polyclonal Antibody
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Catalog No. PIPA5105018
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PIPA5105018 100 μL
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Catalog No. PIPA5105018 Supplier Invitrogen™ Supplier No. PA5105018
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of BLNK only when phosphorylated at Tyrosine 96.

B cell linker protein (Blnk) is a protein encoded by the Blnk gene located on chromosome 10 in humans. It is also known as SLP 65 (Src homology 2 domain-containing leukocyte protein of 65 kDa). It derives its name from being an adaptor protein in the B cell receptor signaling cascade with several supporting studies showing improper development of B cells in the absence of Blnk. Blnk undergoes tyrosine phosphorylation by Syk, a B cell receptor activated kinase, which provides a platform for interaction of signaling intermediaries such as the Vav GEF and Grb2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-BLNK (Tyr96)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BLNK
Gene Accession No. Q8WV28, Q9QUN3
Gene Alias AGM4; B cell adaptor containing SH2 domain; B cell linker; B cell linker protein; BASH; bca; B-cell activation; B-cell adapter containing a SH2 domain protein; B-cell adapter containing a Src homology 2 domain protein; B-cell linker; B-cell linker protein; Blnk; BLNK-S; Cytoplasmic adapter protein; LY57; Ly-57; lymphocyte antigen 57; Lyw-57; MGC111051; SLP65; Slp-65; Src homology [SH2] domain-containing leukocyte protein of 65 kD; Src homology 2 domain-containing leukocyte protein of 65 kDa
Gene Symbols BLNK
Host Species Rabbit
Immunogen A synthesized peptide derived from human BLNK(Accession Q8WV28), corresponding to amino acid residues around phosphorylated Tyr96.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17060, 29760
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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