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Invitrogen™ Phospho-CARD11 (Ser652) Polyclonal Antibody
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Catalog No. PIPA5105228
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PIPA5105228 100 μL
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Catalog No. PIPA5105228 Supplier Invitrogen™ Supplier No. PA5105228
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of CARD11 only when phosphorylated at Ser652.

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-CARD11 (Ser652)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CARD11
Gene Accession No. Q8CIS0, Q9BXL7
Gene Alias 0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL
Gene Symbols CARD11
Host Species Rabbit
Immunogen A synthesized peptide derived from human CARD11(Accession Q9BXL7), corresponding to amino acid residues around phosphorylated Ser652.
Purification Method Sequential chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100363332, 108723, 84433
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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