Phospho-Histone H3 (Ser10) Polyclonal Antibody, Bethyl Laboratories

Catalog No.
50-156-1132	20 μl; Unlabeled

Catalog No. 50-156-1132 Supplier Bethyl Laboratories, Inc Supplier No. A301844AT

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For ICC, formaldehyde fixation and permeabilization with Triton-X 100 is recommended. Acetone fixation may adversely effect staining. For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].

Specifications

• Antigen: Phospho-Histone H3 (Ser10)
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene: HIST1H3A
• Gene Accession No.: P68431, P68433
• Gene Alias: Histone H3, Histone 1, H3a, Histone H3.1, histone H3/a, HIST1H3A
• Gene Symbols: H3c1, HIST1H3A
• Host Species: Rabbit
• Immunogen: Surrounding serine 10
• Purification Method: Antigen affinity chromatography
• Quantity: 20 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 360198, 8350
• Target Species: Human, Mouse
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG