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Phospho-Stat4 (Tyr693) Recombinant Rabbit Monoclonal Antibody (Stat4Y693-F6), Invitrogen™

Catalog No. PIMA528066
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200 μL
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PIMA528066 200 μL
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Catalog No. PIMA528066 Supplier Thermo Scientific Supplier No. MA528066

Description

Rabbit Recombinant Monoclonal Antibody

Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The STAT 4 protein is a transcription factor activated by hormone and cytokines. STAT 4 is most similar to STAT 1 (52%) and STAT 3 (47%). Functionally, STAT 4 is similar to other STAT family members in that it can be tyrosine phosphorylated by JAK 1 or JAK 2. STAT 4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT 4 can bind the interferon g activated site (GAS), and serine phosphorylation is also required for maximal transcriptional activity. STAT 4 expression is restricted to the thymus, spleen, and testis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-STAT4 (Tyr693)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone Stat4Y693-F6
Concentration 0.5 mg/ml
Conjugate Unconjugated
Formulation PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene STAT4
Gene Accession No. P42228, Q14765
Gene Symbols STAT4
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residues surrounding Tyr693 of human phospho Stat4
Purification Method Protein A/G
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20849, 6775
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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