Phospho-Stat6 (Tyr641) Recombinant Rabbit Monoclonal Antibody (Stat6Y641-G12), PE, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA537225	Invitrogen™ MA537225	10 Tests
PIMA536908	Invitrogen™ MA536908	100 Tests

Description

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

Specifications

• Antigen: Phospho-Stat6 (Tyr641)
• Applications: Flow Cytometry
• Conjugate: PE
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P42226, P52633
• Gene ID (Entrez): 20852, 6778
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6.
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Gene: STAT6

• Clone: Stat6Y641-G12
• Classification: Recombinant Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 0.20% BSA and 0.09% sodium azide
• Gene Alias: 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
• Gene Symbols: STAT6
• Isotype: IgG κ
• Purification Method: Protein A/G
• Product Type: Antibody