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PIK3C2A Monoclonal Antibody (OTI4H9), TrueMAB™, OriGene
SDP

Catalog No. 501678935
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100 μL
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Catalog No. Quantity
50-167-8935 100 μL
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Catalog No. 50-167-8935 Supplier OriGene Supplier No. TA801695
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Description

Mouse Monoclonal Antibody

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to omolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.

Specifications

Antigen PIK3C2A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI4H9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene PIK3C2A
Gene Accession No. O00443
Gene Alias CPK, PI3-K-C2(ALPHA), PI3-K-C2A, PI3K-C2-alpha, PI3K-C2alpha
Gene Symbols PIK3C2A
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 230-560 of human PIK3C2A produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5286
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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