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PIN1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501562293
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Catalog No. Quantity
50-156-2293 100 μL
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Catalog No. 50-156-2293 Supplier Bethyl Laboratories, Inc Supplier No. A302315A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Bovine

Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.

Specifications

Antigen PIN1
Applications Immunoprecipitation
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene PIN1
Gene Accession No. Q13526
Gene Alias 0610025L01Rik, D9Bwg1161e, Peptidyl-prolyl cis/trans isomerase
Gene Symbols PIN1
Host Species Rabbit
Immunogen Between 50 and 100
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5300
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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