PITX2 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3320	Active Motif 61304	10 μL
50-199-3319	Active Motif 61303	100 μL

Description

Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.

Specifications

• Antigen: PITX2
• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q99697
• Gene ID (Entrez): 5308
• Immunogen: This PITX2 antibody was raised against a peptide within the N-terminal region of human PITX2.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: PITX2

• Concentration: Lot-Specific
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Alias: 9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; ARP1; BOS_6374; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; Orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; Paired-like homeodomain transcription factor 2; Paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; PITX2; Pitx-2; Pitx2c; Ptx2; RGS; RIEG; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S a 1 glycoprotein; S a1glycoprotein; Solurshin
• Gene Symbols: PITX2
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody