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Tocris Bioscience™ PKUMDL WQ 2101
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Quantity:
25 mg
Description
PKUMDL WQ 2101 is a negative allosteric modulator of phosphoglycerate dehydrogenase (PHGDH) (IC50 = 34.8 μM). Exhibits antitumor activity in vitro in breast cancer cells lines overexpressing PHGDH (EC50 values are 7.7 and 10.8 μM in MDA-MB-468 and HCC-70 cells, respectively). Inhibits growth of MDA-MB-468 xenografts in mice.
Specifications
Specifications
Chemical Name or Material | 2,4-Dihydroxy-N'-(2-hydroxy-5-nitrobenzylidene)benzohydrazide |
CAS | 304481-72-9 |
Quantity | 25 mg |
Molecular Formula | C14H11N3O6 |
Formula Weight | 317.25 |
Purity | 98% |
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