PLA2G4A/cPLA2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-156-9803	Bethyl Laboratories, Inc A305205AT	20 μL

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Orangutan

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Specifications

• Antigen: PLA2G4A/cPLA2
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Alias: cPLA2; calcium-dependent phospholipid-binding protein; cytosolic phospholipase A2; lysophospholipase; phosphatidylcholine 2-acylhydrolase; phospholipase A2 group IVA
• Gene Symbols: PLA2G4A
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody

• Applications: Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: P47712
• Gene ID (Entrez): 5321
• Immunogen: Between 699 and 749
• Primary or Secondary: Primary
• Content And Storage: 4° C
• Gene: PLA2G4A