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Plakophilin 1 Antibody (10B2), DyLight 594, Novus Biologicals™
SDP

Catalog No. NB008331 Shop All R&D Systems Products
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NB008331 0.1 mL
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Catalog No. NB008331 Supplier Novus Biologicals Supplier No. NBP254526DL594
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Description

Mouse Monoclonal Antibody

Plakophilin 1 Monoclonal specifically detects Plakophilin 1 in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

Antigen Plakophilin 1
Applications Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone 10B2
Conjugate DyLight 594
Dilution Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias B6PBand 6 protein, MGC138829, plakophilin 1 (ectodermal dysplasia/skin fragility syndrome), plakophilin-1
Gene Symbols PKP1
Host Species Mouse
Immunogen N-terminus of human Plakophilin 1 protein (Uniprot: Q13835)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cellular Markers
Primary or Secondary Primary
Test Specificity Recognizes a protein of 75kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.
Target Species Human, Mouse
Content And Storage Store at 4°C in the dark.
Isotype IgG1 κ
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