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PMEL17/SILV Antibody (PMEL/783) - IHC-Prediluted, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP248341
Description
PMEL17/SILV Monoclonal specifically detects PMEL17/SILV in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
PMEL17/SILV | |
Monoclonal | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
PMEL | |
Recombinant human PMEL17/SILV protein (Uniprot: P40967) | |
Protein A or G purified | |
RUO | |
6490 | |
Human | |
Purified |
Immunohistochemistry (Paraffin) | |
PMEL/783 | |
Immunohistochemistry-Paraffin | |
D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17 | |
Mouse | |
95 kDa | |
7 mL | |
Primary | |
Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein | |
Store at 4C. | |
IgG1 κ |
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