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PMEL17/SILV Antibody (PMEL/783) - IHC-Prediluted, Novus Biologicals™
SDP

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP248341

Catalog No. NBP248341


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Description

Description

PMEL17/SILV Monoclonal specifically detects PMEL17/SILV in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications

Specifications

PMEL17/SILV
Monoclonal
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
PMEL
Recombinant human PMEL17/SILV protein (Uniprot: P40967)
Protein A or G purified
RUO
6490
Human
Purified
Immunohistochemistry (Paraffin)
PMEL/783
Immunohistochemistry-Paraffin
D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17
Mouse
95 kDa
7 mL
Primary
Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein
Store at 4C.
IgG1 κ
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